Diabetes type 2 insulin level, Global epidemiology of prediabetes - present and future perspectives. - Abstract - Europe PMC
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Dr. Benjamin Bikman - 'Flipping the Switch: From Insulin Resistance to Type 2 Diabetes'
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PMID: Abstract Obesity is associated with lower serum 25 OH D level via several mechanisms including sequestration of fat soluble vitamin D in increased fat mass. Since obesity is the major cause of insulin resistance and type 2 diabetes, lower serum 25 OH D level is also associated with these conditions. Non-surgical weight reduction, especially that results in decreased visceral fat mass, is associated with an improvement in insulin resistance and a small but significant increase in serum 25 OH D level. Whether the latter is independently associated with the former is not known. Plural meta-analyses reported that vitamin D supplementation per se without life-style intervention is not associated with a significant weight reduction.