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Diabetes and metabolism journal impact. Division of Metabolism

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    diabetes and metabolism journal impact

    The Impact Objective: Adiponectin plays an important role in pathophysiology of obesity, type 2 diabetes and cardiovascular disease. The aim of this study was to determine adiponectin concentrations in children and adolescents with type 1 diabetes in a longitudinal manner and to study the impact of age, gender, body mass index BMI and metabolic control. Research design and methods: In this study, 88 children and adolescents with type 1 diabetes were followed longitudinally.

    diabetes and metabolism journal impact

    At baseline and during follow-up, serum levels of adiponectin were measured by enzyme-linked immunoassay and correlated with clinical data, HbA1c and lipids. Results: Serum adiponectin levels were significantly higher in children with type 1 diabetes compared with healthy children Adiponectin concentrations inversely correlated with BMI s.

    No significant difference of adiponectin levels regarding gender, diabetes duration or HbA1c was seen.

    diabetes and metabolism journal impact

    Conclusions: Children and adolescents with type 1 diabetes have BMI-dependent elevated serum concentrations of adiponectin compared with healthy children.